3R Info Bulletins

To date the following 3R Info Bulletins have been published in English:

No.	Date	Topic
56	February 2016	Non-invasive electrical monitoring of the population spiking activity in the central nervous system
55	October 2015	Establishment of a novel system for the production of large numbers of mouse basophils in vitro
54	March 2015	New tools for the generation of peptide- and antibody-based ligands in vitro: Reduction of antibody production in experimental animals
53	Nov. 2014	Genetic manipulation of the human airway epithelium – a paradigmatic system to study host responses to human respiratory viruses
52	June 2014	A new in-vitro approach to the study of brain tumours: an alternative to in-vivo experiments in animals
51	Nov. 2013	Generic in-vitro assays for immunological correlates of protection against foot-and-mouth disease to replace animal challenge infections
50	Dec. 2012	Still relevant twenty-five years on / 25 years of funding the 3Rs - past accomplishments and future prospects
49	June 2012	Bacterial Meningitis: Investigating Injury and Regenerative Therapy in vitro
48	February 2012	A novel ex vivo mouse aorta perfusion model
47	October 2011	Metabolism as part of alternative testing strategies in fish
46	June 2011	Toxoplasma gondii virulence is predictable in cultured human cells
45	February 2011	Serum-free defined media, a largely unsolved problem in cell culture
44	October 2010	From pigs to cells: Virulence of classical swine fever virus is predictable in cell cultures
43	June 2010	Fish, Acute Toxicity Test: The number of animals can be reduced
42	February 2010	The blood-brain barrier in a dish: a new multicellular in vitro model
41	October 2009	A novel in-vitro cell model of the human airway epithelium
40	June 2009	Refined ex-vivo rodent heart model reduces in vivo experimentation
39	February 2009	Detection of Pain in Laboratory Animals via Gene Expression?
38	October 2008	An in-vitro system for detecting the health effects of inhaled particles and gases
37	June 2008	Bioconcentration of chemicals in fish can be assessed in vitro
36	January 2008	Host pathogen interactions can be studied in amoebae instead of animals
35	May 2007	From blood to brain and vice versa: Transport processes in choroid plexus can be studied in vitro
34	January 2007	Exploring natural anticoagulation by endothelial cells: A novel in vitro model
33	Sept. 2006	Predicting drug hypersensitivity by in vitro tests
32	May 2006	Non-Invasive Methods: Investigation of Airways Diseases by MRI in Rats
31	January 2006	Improvement of Pain Therapy in Laboratory Mice
30	Sept. 2005	Environmental enrichment does not disrupt standardization
29	May 2005	Computer-based quantification of (adverse) effects triggered by drugs and chemicals
28	January 2005	Bone metabolism and bone-biomaterial interactions can be studied ex vivo
27	Sept. 2004	The tick blood meal: From a living animal or from a silicone membrane?
26	May 2004	Immune cells in the liver : The generation and use of a mouse Kupffer cell line
25	January 2004	Formation of new blood vessels in the heart can be studied in cell cultures.
24	Sept. 2003	Generation of parasite cysts in cultured cells instead of living animals.
23	May 2003	Simulation of stroke related damage in cultured human nerve cells.
22	January 2003	Environmental enrichment does not affect the variability of animal experimentation data in the Light/Dark test.
21	Sept. 2002	Identification of new human skin irritation markers for tests with human skin reconstructs
20	May 2002	Animal-free screening of biological materials for their contamination by rodent viruses
19	January 2002	Phenotype Characterisation and Welfare Assessment of Transgenic Mice
18	Sept. 2001	Prevention of adverse effects in pigs after vaccination
17	May 2001	Fever in the test tube - towards a human(e) pyrogen test
16	January 2001	Housing and husbandry conditions affect stereotypic behaviour in laboratory gerbils
15	Sept. 2000	Aggregating brain cell cultures: Investigation of stroke related brain damage
14	May 2000	Transgenic protozoa as an alternative to transgenic animals
13	January 2000	Identification of neurotoxic chemicals in cell cultures
12	Sept. 1999	Leishmaniasis: Development of an in vitro assay for drug screening
11	March 1999	Immunization of laboratory animals
10	August 1997	Ten years Foundation Research 3R
9	October 1996	Permanent fish cell cultures as novel tools in environmental toxicology (Fish-cell cultures in environmental toxicology)
8	August 1996	Regulation of digestion in cell culture (Cell culture model for testing digestive processes)
7	March 1996	The three 'R's of Russel & Burch, 1959 (The meaning of the 3 Rs for Russell and Burch, 1959)
6	Sept. 1995	Call for 3R-Research Proposals (Publication of new programme of focal areas)
5	August 1995	Human recombinant antibodies
4	April 1995	Predicting human drug metabollsm (In vitro methods for testing human medication: the use of human liver cells and tissue banks)
3	Dec. 1994	Gerhard Zbinden an 3R (Prof. G. Zbinden and 3R in the field of toxicology: obituary)
2	Sept. 1994	mAbs without mice? (In vitro production of monoclonal antibodies)
1	June 1994	Foundation Research 3R (Presenting the 3R Foundation)