![Méthodes 3R](../../imgs/headers/methods.fr.png)
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Liste des projets
Research Areas | ![](../../imgs/methods/method_M5_thumb.jpg) | Quantitative, non-destructive biofilm analysis on irregular surfaces using microcalorimetry (janvier 2012) This in-vitro approach allows the quantification of biofilm formation on implants, human bone grafts and bone-graft substitutes by means of microcalorimetry. The method has the advantage of allowing the detection of bacterial biomass without removing the biofilm from the surface of the specimen. More... | | ![](../../imgs/methods/method_M6_thumb.png) | Experimental colitis through serial assessment of disease activity by 18F-FDG PET/CT (décembre 2012) Preclinical evaluation of potential drug candidates for human inflammatory bowel disease is performed in murine models of colitis. The most widely used model is dextran-sodium sulfate(DSS)-induced colitis. Non-invasive imaging of murine experimental colitis by Positron emission tomography (PET) combined with radiotracers is feasible and offers the opportunity of serial follow-up investigations. This technique significantly reduces the number of test animals. More... |
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