Projektverzeichnis

ORTHOPEDICS
	Quantitative, non-destructive biofilm analysis on irregular surfaces using microcalorimetry (Januar 2012) This in-vitro approach allows the quantification of biofilm formation on implants, human bone grafts and bone-graft substitutes by means of microcalorimetry. The method has the advantage of allowing the detection of bacterial biomass without removing the biofilm from the surface of the specimen. More...
GASTROENTEROLOGY
	Experimental colitis through serial assessment of disease activity by 18F-FDG PET/CT (Dezember 2012) Preclinical evaluation of potential drug candidates for human inflammatory bowel disease is performed in murine models of colitis. The most widely used model is dextran-sodium sulfate(DSS)-induced colitis. Non-invasive imaging of murine experimental colitis by Positron emission tomography (PET) combined with radiotracers is feasible and offers the opportunity of serial follow-up investigations. This technique significantly reduces the number of test animals. More...