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List of projects
Testing and Diagnosis | | 92-04 | Adjuvanticity of microbial-derived particles and synthetic analogs in vitro.
Padovan E., Prof. Dr., Instituto Gulbenkian de Ciência, Oerias, Portugal
| | | 74-00 | Validation of polymerase chain reaction assays as replacement of the Mouse Antibody Production (MAP) Test
Bootz F., Dr., Institute of Laboratory Animal Science, University of Zürich, Switzerland
| | | 141-14 | In-vitro alternatives to in-vivo bioconcentration-testing in fish: restricted to rainbow trout or broadly applicable ?
Segner, H., Prof., Centre for Fish and Wildlife Health, Vetsuisse Faculty, University of Bern, Switzerland
| | 108-07 | Cultured piscine hepatocytes as an in-vitro source of metabolic clearance data that is currently gleaned by in-vivo bioaccumulation testing in fish
Segner H., Prof. Dr., Centre for Fish and Wildlife Health, Vetsuisse Faculty, University of Berne, Switzerland
| | 100-06 | Development of an in-vitro system for modeling bioaccumulation of neutral, ionizable, and metabolically active organic pollutants in fish
Escher B., Prof. Dr., Dept. of Environmental Toxicology, EAWAG, Dübendorf, Switzerland
| | | | | | 85-03 | Development of an in vitro culture model to generate Neospora caninum and Toxoplasma gondii oocysts and sporozoites
Hemphill A., Prof. Dr., Institute of Parasitology, Faculty of Vetsuisse and of Medicine, University of Berne, Switzerland
| | | 48-96 | Utilization of a model of culture of human intestinal cell lines for the study of the pathogenicity of different strains of Clostridium difficile
Kraehenbuhl J.-P., Prof. Dr., Institut Suisse de Recherches Expérimentales sur le Cancer (ISREC), Switzerland
| | | 84-02 | Direct cloning of human antibodies from purified specific B-cells
Wirthmueller U., Dr., Institute of Immunology, University Hospital Bern, Switzerland
| | | 85-03 | Development of an in vitro culture model to generate Neospora caninum and Toxoplasma gondii oocysts and sporozoites
Hemphill A., Prof. Dr., Institute of Parasitology, Faculty of Vetsuisse and of Medicine, University of Berne, Switzerland
| | 79-01 | Screening methods for repellents and attachment deterrents for ticks in-vitro
Guerin P., PD Dr., Institute of Zoology, University of Neuchâtel, Switzerland
| | 72-00 | Development and applications of an in vitro cultivation model for Neospora caninum tissue cyst formation
Hemphill A., Prof. Dr., Institute of Parasitology, Faculty of Vetsuisse and of Medicine, University of Berne, Switzerland
| | | 52-96 | Development of an interleukin-1 (IL-1) assay with rabbit blood as an alternative to the rabbit pyrogen test
Hartung T., Prof.. Dr., Biochemical Pharmacology, University of Konstanz, Germany
| | | 113-08 | Generic in-vitro evaluation assay for immunological correlates of protection to replace animal challenge infections
Summerfield A., Dr., Institute of Virology and Immunoprophylaxis (IVI), Mittelhaeusern, Switzerland
| | 85-03 | Development of an in vitro culture model to generate Neospora caninum and Toxoplasma gondii oocysts and sporozoites
Hemphill A., Prof. Dr., Institute of Parasitology, Faculty of Vetsuisse and of Medicine, University of Berne, Switzerland
| | 72-00 | Development and applications of an in vitro cultivation model for Neospora caninum tissue cyst formation
Hemphill A., Prof. Dr., Institute of Parasitology, Faculty of Vetsuisse and of Medicine, University of Berne, Switzerland
| | 51-96 | Establishment of endotoxin limits in porcine vaccines: animal welfare aspects
Cussler K., Dr., Paul Ehrlich Institut, Langen, Germany
| | | 74-00 | Validation of polymerase chain reaction assays as replacement of the Mouse Antibody Production (MAP) Test
Bootz F., Dr., Institute of Laboratory Animal Science, University of Zürich, Switzerland
| | 45-96 | Replacement of mouse and rat antibody production test by polymerase chain reaction assays
Homberger F., Prof. Dr., Department of Microbiology and Immunology, Weill Medical College of Cornell University and the Memorial Sloaan-Kettering Center, USA
| | | 133-12 | Development of an in vitro system to grow and investigate vascular endothelial cells under physiological flow conditions
Rieben R., Prof., Department of Clinical Research, University of Bern, Switzerland
| | 111-08 | Establishment of an organ ex-vivo tissue slice model for cardiovascular research in particular for therapeutic atherosclerosis targeting
Hunziker P., PD Dr., Intensive Care Unit, University Hospital Basel, Switzerland
| | 110-08 | Development of an in-vitro assay for the screening of antischistosomal drugs
Keiser J., Prof. Dr., Swiss Tropical Institute, University of Basel,Switzerland
| | 100-06 | Development of an in-vitro system for modeling bioaccumulation of neutral, ionizable, and metabolically active organic pollutants in fish
Escher B., Prof. Dr., Dept. of Environmental Toxicology, EAWAG, Dübendorf, Switzerland
| | 82-02 | Magnetic Resonance Imaging (MRI) for the non-invasive assessment of lung inflammation and pulmonary function in the rat
Beckmann N., PD Dr., Novartis Pharma AG Basel
Novartis Institute of Biomedical Research (NIBR), Basel, Switzerland
| | 81-02 | In vitro model for the testing of endothelial cell activation and damage in whole blood
Rieben R., Prof. Dr., Heart Transplantation Laboratory, Cardiology, University Hospital Bern, Switzerland
| | | 128-11 | Genetic modification of the human airway epithelium – a paradigmatic system to study host responses to human respiratory viruses
Thiel V., PD Dr., Institut für Immunbiologie, Kantonsspital St. Gallen, Switzerland
| | 124-10 | Comparative in vitro and in vivo testing on biofilm formation on the surface of bone grafts
Clauss M., Dr., Kantonsspital Liestal, Orthopädie, Liestal, Switzerland
| | 118-10 | Engineering of an in vitro hepatocyte tissue system for malaria liver infection research
Mancama D., Dr., Systems Biology, Biosciences Unit, CSIR, South Africa
| | 107-07 | Evaluation of an in vitro model to identify host parameters associated with virulence of Toxoplasma gondii strains
D’Souza S., Dr., Pasteur Institute of Brussels-ISP,1180-Uccle, Belgium
| | 99-05 | The NEMO network
(Non-mammalian Experimental Models for the study of bacterial infections)
Cosson P., Prof. Dr., Département de Physiologie Cellulaire et Métabolisme, Centre Medical Universitaire Genève, Geneva 4, Switzerland
| | 90-03 | A non-mammalian system to study bacterial infections
Cosson P., Prof. Dr., Centre Medical Universitaire, Dpt de Morphologie, Geneva 4, Switzerland
| | | 141-14 | In-vitro alternatives to in-vivo bioconcentration-testing in fish: restricted to rainbow trout or broadly applicable ?
Segner, H., Prof., Centre for Fish and Wildlife Health, Vetsuisse Faculty, University of Bern, Switzerland
| | | 136-13 | Development of an in-vitro potency assay for the Clostridium chauvoei vaccines: Replacement of the guinea-pig-challenge potency test
Frey, J., Prof., Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Switzerland
| | | | 109-08 | Evaluation of lipid fractions for the substitution of serum in cell culture media
Honegger P., Prof. Dr., Département de Physiologie, Université de Lausanne, Switzerland
| | 77-01 | Reproducibility and external validity of findings from animal experiments: influence of housing conditions
Würbel H., Prof. Dr., Institute of Laboratory Animal Science, University of Zurich, Switzerland
| | | | 106-07 | Standardization and Pre-validation of MucilAir: A novel in vitro cell model of the human airway epithelium for testing acute and chronic effects of chemical compounds
Huang S., Dr., Epithelix Sàrl, Plan-les-Ouates, Geneva, Switzerland
| | 89-03 | In vitro replica of the inner surface of the lungs, for the study of particle-cell interaction
Geiser Kamber M., Prof. Dr., Institute of Anatomy, University of Bern, Switzerland
| | | | | 94-04 | Tumor targeted reporter gene expression to improve and refine traditional models of Tumor growth and metastasis
Vorburger S., Dr., Department of Clinical Research, Visceral and Transplantation Surgery,
University Hospital Bern, Switzerland
| | | | 67-99 | Human monocyte-derived dendritic cells as in vitro indicators for contact allergic potential of chemicals
Ulrich P., Dr., PCS/GENEX-Experimental Toxicology, Novartis Pharma AG, Basel, Switzerland
| | | | | 89-03 | In vitro replica of the inner surface of the lungs, for the study of particle-cell interaction
Geiser Kamber M., Prof. Dr., Institute of Anatomy, University of Bern, Switzerland
| | | 138-13 | Optimization of the nerve-cell-mimicking liposome assay as an in-vitro alternative for the detection of Clostridium-botulinum neurotoxins and for a validation of their presence in complex sample materials
Avondet, M.-A., Toxinology Group, Spiez Laboratory, Switzerland
| | 125-11 | Nerve-cell mimicking liposomes as in vitro alternative to potency-testing of toxins with multistep pathways, such as Botulinum neurotoxins
Weingart O.G., Dr., Institute for Food, Nutrition and Health (IFNH), ETH Zurich, Switzerland;
| | | 125-11 | Nerve-cell mimicking liposomes as in vitro alternative to potency-testing of toxins with multistep pathways, such as Botulinum neurotoxins
Weingart O.G., Dr., Institute for Food, Nutrition and Health (IFNH), ETH Zurich, Switzerland;
| | 75-00 | Internet laboratory for predicting harmful effects triggered by drugs and chemicals
Vedani A., Prof. Dr., Biographics Laboratory 3R, Basel, Switzerland
present address: Department of Chemistry, Molecular Modeling. University of Basel, Pharmacenter, 4056 Basel, Switzerland
| | 60-97 | Transgenic protozoa (Trypanosoma spp.) as an alternative to transgenic animals
Roditi I., Prof. Dr., Institutes of General Microbiology and Parasitology, University of Bern, Switzerland
| | 55-96 | Computer-aided identification of ochratoxin antagonists
Vedani A., Prof. Dr., Biographics Laboratory 3R, Basel, Switzerland
| | 54-96 | Elaboration of an in vitro screening method for testing the effect of drugs and other compounds on the renal transport of uric acid
Roch-Ramel F., Prof. Dr., Institute of Pharmacoly and Toxicology, University of Lausanne, Switzerland
| | 53-96 | Axenic cultivation of amastigote forms of Leishmania
Grimm F., Dr. phil. nat., Institute of Parasitology, University of Zürich, Switzerland
| | 50-96 | Morphometric Analysis of human articular cartilage
Hunziker E., Prof. Dr., M.E.Müller Institut für Biomechanik, University of Bern, Switzerland
| | | 125-11 | Nerve-cell mimicking liposomes as in vitro alternative to potency-testing of toxins with multistep pathways, such as Botulinum neurotoxins
Weingart O.G., Dr., Institute for Food, Nutrition and Health (IFNH), ETH Zurich, Switzerland;
| | 75-00 | Internet laboratory for predicting harmful effects triggered by drugs and chemicals
Vedani A., Prof. Dr., Biographics Laboratory 3R, Basel, Switzerland
present address: Department of Chemistry, Molecular Modeling. University of Basel, Pharmacenter, 4056 Basel, Switzerland
| | | 67-99 | Human monocyte-derived dendritic cells as in vitro indicators for contact allergic potential of chemicals
Ulrich P., Dr., PCS/GENEX-Experimental Toxicology, Novartis Pharma AG, Basel, Switzerland
| | | 70-99 | Sensory irritant screening using a stable cell line expressing the vanilloid receptor
Baumann T., Prof. Dr., Dept. of Neurological Suregry,Oregon Health and Sciences University, Portland, USA
| | | 75-00 | Internet laboratory for predicting harmful effects triggered by drugs and chemicals
Vedani A., Prof. Dr., Biographics Laboratory 3R, Basel, Switzerland
present address: Department of Chemistry, Molecular Modeling. University of Basel, Pharmacenter, 4056 Basel, Switzerland
| | 55-96 | Computer-aided identification of ochratoxin antagonists
Vedani A., Prof. Dr., Biographics Laboratory 3R, Basel, Switzerland
| | 47-96 | Development of an in vitro system for the detection of estrogenic compounds (xenoestrogens)
Fent K., PD Dr., Swiss Federal Institute for Environmental Science and Technology (EAWAG), Switzerland
| | 43-95 | Short term assay for liver cell activated neurotoxic drugs
Maier P., Prof. Dr., Institute of Toxicology, Swiss Federal Institute of Technology (ETH) and University of Zürich, Switzerland
| | | 69-99 | A human neural cell line as in vitro model system for the excitotoxic cascade during stroke
Bicker G., Prof. Dr., Abt. Zellbiologie, Physiologisches Institut, Stiftung Tierärztliche Hochschule Hannover, Germany
| | | 138-13 | Optimization of the nerve-cell-mimicking liposome assay as an in-vitro alternative for the detection of Clostridium-botulinum neurotoxins and for a validation of their presence in complex sample materials
Avondet, M.-A., Toxinology Group, Spiez Laboratory, Switzerland
| | 137-13 | Validation of a new human in-vitro model of microglia
Filgueira, L., Prof., Department of Medicine, University of Fribourg, Switzerland
| | 106-07 | Standardization and Pre-validation of MucilAir: A novel in vitro cell model of the human airway epithelium for testing acute and chronic effects of chemical compounds
Huang S., Dr., Epithelix Sàrl, Plan-les-Ouates, Geneva, Switzerland
| | 86-03 | Bone Formation in a loading chamber for ex-vivo bone culture
Richards R.G., Dr., AO Research Institute, Davos, Switzerland
| | 78-01 | Validation of a combined perfusion/loading chamber for ex-vivo bone metabolic studies and bone-biomaterial interactions
Richards R.G., Dr., AO Research Institute, Davos, Switzerland
| | | 105-06 | Establishment of an in vitro system for the prediction of the degree of virulence of classical swine fever virus isolates
Ruggli N., Dr., Institute of Virology and Immunoprophylaxis (IVI), Mittelhaeusern, Switzerland
| | 85-03 | Development of an in vitro culture model to generate Neospora caninum and Toxoplasma gondii oocysts and sporozoites
Hemphill A., Prof. Dr., Institute of Parasitology, Faculty of Vetsuisse and of Medicine, University of Berne, Switzerland
| | 79-01 | Screening methods for repellents and attachment deterrents for ticks in-vitro
Guerin P., PD Dr., Institute of Zoology, University of Neuchâtel, Switzerland
| | 72-00 | Development and applications of an in vitro cultivation model for Neospora caninum tissue cyst formation
Hemphill A., Prof. Dr., Institute of Parasitology, Faculty of Vetsuisse and of Medicine, University of Berne, Switzerland
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