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List of projects
ANALGESIA | |
| Detection and characterisation of signs of pain in mice by the combined use of a telemetry model and behavioural observations Arras M., Dr., Institute of Laboratory Animal Science, University of Zürich, Switzerland | |
ANESTHESIA | |
ANIMAL WELFARE | |
| Improved perioperative analgesia and reduced stress during recovery for the experimental animal: ultrasound-guided sciatic and femoral nerve block in sheep and quantitative assessment of block quality Rohrbach H., Dr, Institute for Anaesthesiology and Pain Therapy, Vetsuisse Faculty, University of Bern, Switzerland | |
| Assessing animal health and welfare and recognising pain and distress Flecknell P., Prof. Dr., Comparative Biology Centre, University of Newcastle, UK | |
ANGIOGENESIS | |
| An in-vitro microvascular model of the endothelial barrier Herrmann, M., Dr., AO Research Institute Davos, Switzerland | |
| Embryonic stem-cell-derived in-vitro model of tissue inflammation following confrontation with implant materials Wartenberg M., Prof. Dr., Friedrich Schiller University Jena and Justus Liebig University Giessen, Germany | |
| Development of a model of heart angiogenesis in vitro Battegay E., Prof. Dr., Outpatient Department of Internal Medicine and Department of Research, University Hospital Basel, Switzerland | |
BYPASS GRAFT STENOSIS | |
| An in vitro model to study mechanical forces on human venous coronary bypass graft stenosis: Molecular targeting by pharmacological intervention Lüscher T. F., Prof. Dr., Cardiovascular Research, Institute of Physiology, University Zürich and Cardiology, University Hospital Zürich, Switzerland | |
CHEMICAL RISK ASSESSMENT | |
| Combining computational modelling with in-vitro cellular responses in order to predict chemical impact on fish growth Schirmer, K., Prof. Dr., EAWAG, Swiss Federal Institute of Aquatic Science and Technology, Dübendorf, Switzerland | |
CNS, BRAIN DISORDERS | |
| Hydrocephalus simulator for testing of active ventriculoperitoneal shunts Schmid Daners, M., Dr., Institute for Dynamic Systems and Control, Department of Mechanical and Process Engineering, ETH Zurich, Switzerland | |
| Development of a novel multicellular 3-dimensional blood brain barrier in vitro model Ogunshola O., Dr., Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zürich, Switzerland | |
COAGULATION | |
| Development of an in vitro system to grow and investigate vascular endothelial cells under physiological flow conditions Rieben R., Prof., Department of Clinical Research, University of Bern, Switzerland | |
| In vitro model for the testing of endothelial cell activation and damage in whole blood Rieben R., Prof. Dr., Heart Transplantation Laboratory, Cardiology, University Hospital Bern, Switzerland | |
COMPLEMENT SYSTEM | |
| In vitro model for the testing of endothelial cell activation and damage in whole blood Rieben R., Prof. Dr., Heart Transplantation Laboratory, Cardiology, University Hospital Bern, Switzerland | |
CYTOKINES, GROWTH FACTORS | |
| Adjuvanticity of microbial-derived particles and synthetic analogs in vitro. Padovan E., Prof. Dr., Instituto Gulbenkian de Ciência, Oerias, Portugal | |
| Transgenic protozoa (Trypanosoma spp.) as an alternative to transgenic animals Roditi I., Prof. Dr., Institutes of General Microbiology and Parasitology, University of Bern, Switzerland | |
| Development of an interleukin-1 (IL-1) assay with rabbit blood as an alternative to the rabbit pyrogen test Hartung T., Prof.. Dr., Biochemical Pharmacology, University of Konstanz, Germany | |
| Establishment of endotoxin limits in porcine vaccines: animal welfare aspects Cussler K., Dr., Paul Ehrlich Institut, Langen, Germany | |
| Development and Validation of an In Vitro Model Simulating Mechanical Ventilation-Induced Inflammation Pugin J., Dr., Division des Soins Intensifs de Médecine, Hôpital Cantonal Universitaire, Genève, Suisse | |
DRUG-DESIGN | |
| Internet laboratory for predicting harmful effects triggered by drugs and chemicals Vedani A., Prof. Dr., Biographics Laboratory 3R, Basel, Switzerland present address: Department of Chemistry, Molecular Modeling. University of Basel, Pharmacenter, 4056 Basel, Switzerland | |
| Computer-aided identification of ochratoxin antagonists Vedani A., Prof. Dr., Biographics Laboratory 3R, Basel, Switzerland | |
ECOTOXICOLOGY | |
| Use of "moribund" stage in the acute fish toxicity test according to OECD guideline 203 and its effect on LC50 values Rufli H., Dr., ecotoxsolution, Basel, Switzerland | |
| Reduction of the number of animals used in the Fish Acute Toxicity Test Rufli H., Dr., ecotoxsolution, Basel, Switzerland | |
| Cultured piscine hepatocytes as an in-vitro source of metabolic clearance data that is currently gleaned by in-vivo bioaccumulation testing in fish Segner H., Prof. Dr., Centre for Fish and Wildlife Health, Vetsuisse Faculty, University of Berne, Switzerland | |
| Development of an in-vitro system for modeling bioaccumulation of neutral, ionizable, and metabolically active organic pollutants in fish Escher B., Prof. Dr., Dept. of Environmental Toxicology, EAWAG, Dübendorf, Switzerland | |
ETHOLOGY | |
ETHOLOGY: LABORATORY ANIMALS | |
| Reproducibility and external validity of findings from animal experiments: influence of housing conditions Würbel H., Prof. Dr., Institute of Laboratory Animal Science, University of Zurich, Switzerland | |
| Detection and characterisation of signs of pain in mice by the combined use of a telemetry model and behavioural observations Arras M., Dr., Institute of Laboratory Animal Science, University of Zürich, Switzerland | |
| The influence of enriched housing conditions on experimental results in laboratory mice Baumans V., Prof. Dr., Department of Laboratory Animal Science, University of Utrecht, Netherland | |
| Phenotype characterisation and health monitoring of transgenic mice Mertens C., dipl. phil. nat., Zürcher Tierschutz (SPCA), Zürich, Switzerland | |
| Development of laboratory housing conditions preventing stereotypic behaviour in Mongolian gerbils (Meriones unguiculatus) König B., Prof. Dr., Department of Animal Behaviour, Institute of Zoology, University of Zürich, Switzerland | |
| Laboratory animal husbandry and welfare - Key strategic goals of future research Würbel H., Prof. Dr., Institute of Animal Sciences, Physiology and Animal Husbandry, Swiss Federal Institute of Technology (ETH), Switzerland | |
ETHOLOGY: TRANSGENIC ANIMALS | |
| Phenotype characterisation and health monitoring of transgenic mice Mertens C., dipl. phil. nat., Zürcher Tierschutz (SPCA), Zürich, Switzerland | |
ETHOLOGY: ENRICHMENT | |
| The influence of enriched housing conditions on experimental results in laboratory mice Baumans V., Prof. Dr., Department of Laboratory Animal Science, University of Utrecht, Netherland | |
| Development of laboratory housing conditions preventing stereotypic behaviour in Mongolian gerbils (Meriones unguiculatus) König B., Prof. Dr., Department of Animal Behaviour, Institute of Zoology, University of Zürich, Switzerland | |
HEART VALVES | |
| Cardiovascular simulator with autoregulation Vandenberghe S,, Prof., ARTORG Center for Biomedical Research, University of Bern, Switzerland | |
IMMUNOLOGY | |
| Validation of a new human in-vitro model of microglia Filgueira, L., Prof., Department of Medicine, University of Fribourg, Switzerland | |
| Establishing a novel system for quantitative production of murine basophils in vitro Kaufmann T., PD Dr., Institute of Pharmacology, University of Bern, Switzerland | |
| Organotypic CNS slice cultures as an in-vitro model for immune mediated tissue damage and repair in multiple sclerosis Goebels N., Prof. Dr., Heinrich-Heine University Düsseldorf Medical Faculty, Department of Neurology | |
| Induction of a primary T cell mediated immune response against drugs and drug metabolites in vitro Pichler, W.J., Prof. Dr., Division Allergology, University Hospital Bern, Switzerland | |
IMMUNOLOGY | |
IMMUNOLOGY: MONOCLONAL ANTIBODY PRODUCTION | |
| Development of a mimotope-based tetanus and diphtheria vaccine Stadler B. M., Prof. Dr., Institute of Immunology and Allergology, Inselspital, University of Berne, Switzerland | |
IN VITRO TESTING | |
| Cardiovascular simulator with autoregulation Vandenberghe S,, Prof., ARTORG Center for Biomedical Research, University of Bern, Switzerland | |
MECHANOBIOLOGY | |
| Establishment of an in-vitro organ-slice defect model for meniscal repair in orthopaedic research Hunziker E., Prof., Center of Regenerative Medicine for Skeletal Tissues, University of Bern, Switzerland | |
| Improved perioperative analgesia and reduced stress during recovery for the experimental animal: ultrasound-guided sciatic and femoral nerve block in sheep and quantitative assessment of block quality Rohrbach H., Dr, Institute for Anaesthesiology and Pain Therapy, Vetsuisse Faculty, University of Bern, Switzerland | |
| The development of an in vitro intervertebral disc organ culture system Lee C., Dr., Biochemistry and Cell Biology Unit; AO Research Institute, Davos, Switzerland | |
NEUROLOGY | |
| Validation of a new human in-vitro model of microglia Filgueira, L., Prof., Department of Medicine, University of Fribourg, Switzerland | |
ORTHOPEDICS | |
| Establishment of an in-vitro organ-slice defect model for meniscal repair in orthopaedic research Hunziker E., Prof., Center of Regenerative Medicine for Skeletal Tissues, University of Bern, Switzerland | |
| Comparative in vitro and in vivo testing on biofilm formation on the surface of bone grafts Clauss M., Dr., Kantonsspital Liestal, Orthopädie, Liestal, Switzerland | |
| Improved perioperative analgesia and reduced stress during recovery for the experimental animal: ultrasound-guided sciatic and femoral nerve block in sheep and quantitative assessment of block quality Rohrbach H., Dr, Institute for Anaesthesiology and Pain Therapy, Vetsuisse Faculty, University of Bern, Switzerland | |
PHARMACOLOGY | |
| Development of a novel multicellular 3-dimensional blood brain barrier in vitro model Ogunshola O., Dr., Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zürich, Switzerland | |
| Establishment and validation of a Choroid Plexus Model to study drug transport Fricker G., Prof. Dr., Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls Universität Heidelberg, Germany | |
| Internet laboratory for predicting harmful effects triggered by drugs and chemicals Vedani A., Prof. Dr., Biographics Laboratory 3R, Basel, Switzerland present address: Department of Chemistry, Molecular Modeling. University of Basel, Pharmacenter, 4056 Basel, Switzerland | |
| A human neural cell line as in vitro model system for the excitotoxic cascade during stroke Bicker G., Prof. Dr., Abt. Zellbiologie, Physiologisches Institut, Stiftung Tierärztliche Hochschule Hannover, Germany | |
| Genetic analysis of a 3D in vitro model of the rheumatic pannus tissue Illges H., PD Dr., Biotechnologie Institut Thurgau an der Universität Konstanz, Switzerland | |
| Computer-aided identification of ochratoxin antagonists Vedani A., Prof. Dr., Biographics Laboratory 3R, Basel, Switzerland | |
| Elaboration of an in vitro screening method for testing the effect of drugs and other compounds on the renal transport of uric acid Roch-Ramel F., Prof. Dr., Institute of Pharmacoly and Toxicology, University of Lausanne, Switzerland | |
| Axenic cultivation of amastigote forms of Leishmania Grimm F., Dr. phil. nat., Institute of Parasitology, University of Zürich, Switzerland | |
| Morphometric Analysis of human articular cartilage Hunziker E., Prof. Dr., M.E.Müller Institut für Biomechanik, University of Bern, Switzerland | |
PHAGOCYTOSIS | |
| Generation and functional characterization of a clonal murine periportal Kupffer cell line from H-2Kb -tsA58 mice Landmann R., Prof. Dr., Division of Infectious Diseases, Department of Research, University Hospital Basel, Switzerland | |
PAIN / STRESS | |
| Improved perioperative analgesia and reduced stress during recovery for the experimental animal: ultrasound-guided sciatic and femoral nerve block in sheep and quantitative assessment of block quality Rohrbach H., Dr, Institute for Anaesthesiology and Pain Therapy, Vetsuisse Faculty, University of Bern, Switzerland | |
| Assessment of pain and stress in mice by monitoring gene expression changes Cinelli P., Dr., Institute of Laboratory Animal Science, University of Zurich, Switzerland | |
QSAR | |
| Development of QSAR-Models for Classification and Prediction of Baseline Toxicity and of Uncoupling of Energy Transduction Spycher S. + Escher B., Prof. Dr., Dept. of Environmental Toxicology, EAWAG, Dübendorf, Switzerland | |
| Internet laboratory for predicting harmful effects triggered by drugs and chemicals Vedani A., Prof. Dr., Biographics Laboratory 3R, Basel, Switzerland present address: Department of Chemistry, Molecular Modeling. University of Basel, Pharmacenter, 4056 Basel, Switzerland | |
| Computer-aided identification of ochratoxin antagonists Vedani A., Prof. Dr., Biographics Laboratory 3R, Basel, Switzerland | |
VETERINARY DRUGS | |
| Establishment of an in vitro system for the prediction of the degree of virulence of classical swine fever virus isolates Ruggli N., Dr., Institute of Virology and Immunoprophylaxis (IVI), Mittelhaeusern, Switzerland | |
| Development of an in vitro culture model to generate Neospora caninum and Toxoplasma gondii oocysts and sporozoites Hemphill A., Prof. Dr., Institute of Parasitology, Faculty of Vetsuisse and of Medicine, University of Berne, Switzerland | |
| Screening methods for repellents and attachment deterrents for ticks in-vitro Guerin P., PD Dr., Institute of Zoology, University of Neuchâtel, Switzerland | |
| Development and applications of an in vitro cultivation model for Neospora caninum tissue cyst formation Hemphill A., Prof. Dr., Institute of Parasitology, Faculty of Vetsuisse and of Medicine, University of Berne, Switzerland | |
TUMOURIGENESIS | |
| Engineering of a human brain tumour model to replace animal experimentation Preynat-Seauve O., Dr., University of Geneva, Switzerland | |
| Tumor targeted reporter gene expression to improve and refine traditional models of Tumor growth and metastasis Vorburger S., Dr., Department of Clinical Research, Visceral and Transplantation Surgery, University Hospital Bern, Switzerland | |
TOXICOLOGY | |
| Optimization of the nerve-cell-mimicking liposome assay as an in-vitro alternative for the detection of Clostridium-botulinum neurotoxins and for a validation of their presence in complex sample materials Avondet, M.-A., Toxinology Group, Spiez Laboratory, Switzerland | |
| Nerve-cell mimicking liposomes as in vitro alternative to potency-testing of toxins with multistep pathways, such as Botulinum neurotoxins Weingart O.G., Dr., Institute for Food, Nutrition and Health (IFNH), ETH Zurich, Switzerland; | |
| Standardization and Pre-validation of MucilAir: A novel in vitro cell model of the human airway epithelium for testing acute and chronic effects of chemical compounds Huang S., Dr., Epithelix Sàrl, Plan-les-Ouates, Geneva, Switzerland | |
| Development of QSAR-Models for Classification and Prediction of Baseline Toxicity and of Uncoupling of Energy Transduction Spycher S. + Escher B., Prof. Dr., Dept. of Environmental Toxicology, EAWAG, Dübendorf, Switzerland | |
| In vitro replica of the inner surface of the lungs, for the study of particle-cell interaction Geiser Kamber M., Prof. Dr., Institute of Anatomy, University of Bern, Switzerland | |
| Elaboration of an in vitro screening method for testing the effect of drugs and other compounds on the renal transport of uric acid Roch-Ramel F., Prof. Dr., Institute of Pharmacoly and Toxicology, University of Lausanne, Switzerland | |
| Axenic cultivation of amastigote forms of Leishmania Grimm F., Dr. phil. nat., Institute of Parasitology, University of Zürich, Switzerland | |
| Development of an in vitro system for the detection of estrogenic compounds (xenoestrogens) Fent K., PD Dr., Swiss Federal Institute for Environmental Science and Technology (EAWAG), Switzerland | |
| Short term assay for liver cell activated neurotoxic drugs Maier P., Prof. Dr., Institute of Toxicology, Swiss Federal Institute of Technology (ETH) and University of Zürich, Switzerland | |
TRANSPLANTATION | |
| Development of an in vitro system to grow and investigate vascular endothelial cells under physiological flow conditions Rieben R., Prof., Department of Clinical Research, University of Bern, Switzerland | |
| Identification of predictive in vitro markers of hematopoietic stem cell function Lutolf M. P., Prof., Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland | |
| An in vitro Model of Central Nervous System Infection and Regeneration: Neuronal Stem Cells as Targets of Brain Damage & Regenerative Therapies in Bacterial Meningitis. Leib S.L., Prof. Dr., Institute of Infectious Diseases, University of Bern, Switzerland | |
| Isolated, autologous blood-perfused heart: Replacement of heterotopic heart transplantation Bogdanova A, Dr., Institute of Veterinary Physiology, University of Zurich, Switzerland | |
| In vitro model for the testing of endothelial cell activation and damage in whole blood Rieben R., Prof. Dr., Heart Transplantation Laboratory, Cardiology, University Hospital Bern, Switzerland | |
VACCINATION | |
| Development of an in-vitro potency assay for the Clostridium chauvoei vaccines: Replacement of the guinea-pig-challenge potency test Frey, J., Prof., Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Switzerland | |
| Generic in-vitro evaluation assay for immunological correlates of protection to replace animal challenge infections Summerfield A., Dr., Institute of Virology and Immunoprophylaxis (IVI), Mittelhaeusern, Switzerland | |
| Development of in vitro strategies to propagate and characterize hemotrophic mycoplasmas Hofmann-Lehmann R., Prof. Dr., Clinical Laboratory, Vetsuisse-Faculty, University of Zurich, Switzerland | |
| Adjuvanticity of microbial-derived particles and synthetic analogs in vitro. Padovan E., Prof. Dr., Instituto Gulbenkian de Ciência, Oerias, Portugal | |
| Development of an in vitro culture model to generate Neospora caninum and Toxoplasma gondii oocysts and sporozoites Hemphill A., Prof. Dr., Institute of Parasitology, Faculty of Vetsuisse and of Medicine, University of Berne, Switzerland | |
VETERINARY DRUGS | |
| Establishment of an in vitro system for the prediction of the degree of virulence of classical swine fever virus isolates Ruggli N., Dr., Institute of Virology and Immunoprophylaxis (IVI), Mittelhaeusern, Switzerland | |
| Development of an in vitro culture model to generate Neospora caninum and Toxoplasma gondii oocysts and sporozoites Hemphill A., Prof. Dr., Institute of Parasitology, Faculty of Vetsuisse and of Medicine, University of Berne, Switzerland | |
| Screening methods for repellents and attachment deterrents for ticks in-vitro Guerin P., PD Dr., Institute of Zoology, University of Neuchâtel, Switzerland | |
| Development and applications of an in vitro cultivation model for Neospora caninum tissue cyst formation Hemphill A., Prof. Dr., Institute of Parasitology, Faculty of Vetsuisse and of Medicine, University of Berne, Switzerland | |
| Last modified 2018/10/12 |  |