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List of projects
Organs and Tissues | | 129-11 | The use of microfluidic chambers to study axonal transport in PTEN and SOCS3 dependent axonal regeneration
He Zhigang, Prof., Children's Hospital and Department of Neurology, Harvard Medical School, Boston, MA 02115
| | | 93-04 | Development of a novel multicellular 3-dimensional blood brain barrier in vitro model
Ogunshola O., Dr., Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zürich, Switzerland
| | | 104-06 | Development of in vitro strategies to propagate and characterize hemotrophic mycoplasmas
Hofmann-Lehmann R., Prof. Dr., Clinical Laboratory, Vetsuisse-Faculty, University of Zurich, Switzerland
| | 81-02 | In vitro model for the testing of endothelial cell activation and damage in whole blood
Rieben R., Prof. Dr., Heart Transplantation Laboratory, Cardiology, University Hospital Bern, Switzerland
| | 52-96 | Development of an interleukin-1 (IL-1) assay with rabbit blood as an alternative to the rabbit pyrogen test
Hartung T., Prof.. Dr., Biochemical Pharmacology, University of Konstanz, Germany
| | | 127-11 | Establishing a novel system for quantitative production of murine basophils in vitro
Kaufmann T., PD Dr., Institute of Pharmacology, University of Bern, Switzerland
| | | | | 111-08 | Establishment of an organ ex-vivo tissue slice model for cardiovascular research in particular for therapeutic atherosclerosis targeting
Hunziker P., PD Dr., Intensive Care Unit, University Hospital Basel, Switzerland
| | | 130-11 | Establishment of an in-vitro organ-slice defect model for meniscal repair in orthopaedic research
Hunziker E., Prof., Center of Regenerative Medicine for Skeletal Tissues, University of Bern, Switzerland
| | 112-08 | A novel in-vitro model for the holistic assessment and optimisation of engineered tissue for functional cartilage repair
Luo Z., Dr., Leeds Dental Institute, Leeds LS9 9LU, UK
| | 86-03 | Bone Formation in a loading chamber for ex-vivo bone culture
Richards R.G., Dr., AO Research Institute, Davos, Switzerland
| | 78-01 | Validation of a combined perfusion/loading chamber for ex-vivo bone metabolic studies and bone-biomaterial interactions
Richards R.G., Dr., AO Research Institute, Davos, Switzerland
| | 62-97 | Development of an in vitro model system for cartilage invasion by synovial fibroblasts
Gay R. E., Prof. Dr., Department of Rheumatology, University Hospital Zürich, Switzerland
| | 50-96 | Morphometric Analysis of human articular cartilage
Hunziker E., Prof. Dr., M.E.Müller Institut für Biomechanik, University of Bern, Switzerland
| | | 146-15 | Validation of a novel cell-based approach to study thyroidal physiology: Reduction and/or replacement of experiments with rodents
Sykiotis, G., PhD, Service of Endocrinology, Diabetology and Metabolism, Lausanne University Hospital, Lausanne, Switzerland
| | | 137-13 | Validation of a new human in-vitro model of microglia
Filgueira, L., Prof., Department of Medicine, University of Fribourg, Switzerland
| | 119-10 | Non invasive electrical monitoring of the population spiking activity in the central nervous system
Gonzalez Andino S.L., Dr., University of Geneva and Geneva University Hospital, Switzerland
| | 116-09 | Organotypic brain-slice cultures derived from regularly-slaughtered animals as an in-vitro alternative for the investigation of neuroinfectious diseases in ruminants
Oevermann A., Dr., Vetsuisse Faculty, University of Berne, Switzerland
| | 115-09 | Engineering of a human brain tumour model to replace animal experimentation
Preynat-Seauve O., Dr., University of Geneva, Switzerland
| | 109-08 | Evaluation of lipid fractions for the substitution of serum in cell culture media
Honegger P., Prof. Dr., Département de Physiologie, Université de Lausanne, Switzerland
| | 103-06 | An in vitro Model of Central Nervous System Infection and Regeneration: Neuronal Stem Cells as Targets of Brain Damage & Regenerative Therapies in Bacterial Meningitis.
Leib S.L., Prof. Dr., Institute of Infectious Diseases, University of Bern, Switzerland
| | 101-06 | Organotypic CNS slice cultures as an in-vitro model for immune mediated tissue damage and repair in multiple sclerosis
Goebels N., Prof. Dr., Heinrich-Heine University Düsseldorf
Medical Faculty, Department of Neurology
| | 96-05 | Assessment of pain and stress in mice by monitoring gene expression changes
Cinelli P., Dr., Institute of Laboratory Animal Science, University of Zurich, Switzerland
| | 93-04 | Development of a novel multicellular 3-dimensional blood brain barrier in vitro model
Ogunshola O., Dr., Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zürich, Switzerland
| | 91-04 | Establishment and validation of a Choroid Plexus Model to study drug transport
Fricker G., Prof. Dr., Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls Universität Heidelberg, Germany
| | 69-99 | A human neural cell line as in vitro model system for the excitotoxic cascade during stroke
Bicker G., Prof. Dr., Abt. Zellbiologie, Physiologisches Institut, Stiftung Tierärztliche Hochschule Hannover, Germany
| | 64-97 | Use of three-dimensional brain cell cultures as a model for ischemia-related research
Honegger P., Prof. Dr., Institute of Physiology, Faculty of Medicine, University of Lausanne, Switzerland
| | 44-95 | Establishment of a micro technique for corticosteroid receptor binding studies
Hügin-Flores M., Dr., Psychopharmacology Unit, Department of Psychiatry, University Hospital, Geneva, Switzerland
| | 43-95 | Short term assay for liver cell activated neurotoxic drugs
Maier P., Prof. Dr., Institute of Toxicology, Swiss Federal Institute of Technology (ETH) and University of Zürich, Switzerland
| | | 135-13 | In-vitro engineering of a human cell-based threedimensional dynamic model of atherosclerosis
Weber, B, Dr. Dr., Swiss Center for Regenerative Medicine, University Hospital Zurich, Switzerland
| | | 139-14 | An in-vitro microvascular model of the endothelial barrier
Herrmann, M., Dr., AO Research Institute Davos, Switzerland
| | 135-13 | In-vitro engineering of a human cell-based threedimensional dynamic model of atherosclerosis
Weber, B, Dr. Dr., Swiss Center for Regenerative Medicine, University Hospital Zurich, Switzerland
| | | 144-15 | Development of in vitro three-dimensional multi-cellular culture models to study the role of heterotypic interactions during colorectal carcinomatous invasive process
Rüegg, C., Prof. Dr., Department of OMI, University of Fribourg, Switzerland
| | | | 91-04 | Establishment and validation of a Choroid Plexus Model to study drug transport
Fricker G., Prof. Dr., Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls Universität Heidelberg, Germany
| | | 92-04 | Adjuvanticity of microbial-derived particles and synthetic analogs in vitro.
Padovan E., Prof. Dr., Instituto Gulbenkian de Ciência, Oerias, Portugal
| | 67-99 | Human monocyte-derived dendritic cells as in vitro indicators for contact allergic potential of chemicals
Ulrich P., Dr., PCS/GENEX-Experimental Toxicology, Novartis Pharma AG, Basel, Switzerland
| | | 142-14 | Validation of human stem-cell pluripotency using a bioreactor-based culturing system instead of a murine model to effect the development of embryoid bodies into teratomas
De Geyter, C., Prof. Dr., Department of Biomedicine, Department of Biomedicine, University Hospital, University of Basel, Switzerland
| | | 128-11 | Genetic modification of the human airway epithelium – a paradigmatic system to study host responses to human respiratory viruses
Thiel V., PD Dr., Institut für Immunbiologie, Kantonsspital St. Gallen, Switzerland
| | 107-07 | Evaluation of an in vitro model to identify host parameters associated with virulence of Toxoplasma gondii strains
D’Souza S., Dr., Pasteur Institute of Brussels-ISP,1180-Uccle, Belgium
| | 106-07 | Standardization and Pre-validation of MucilAir: A novel in vitro cell model of the human airway epithelium for testing acute and chronic effects of chemical compounds
Huang S., Dr., Epithelix Sàrl, Plan-les-Ouates, Geneva, Switzerland
| | 93-04 | Development of a novel multicellular 3-dimensional blood brain barrier in vitro model
Ogunshola O., Dr., Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zürich, Switzerland
| | 91-04 | Establishment and validation of a Choroid Plexus Model to study drug transport
Fricker G., Prof. Dr., Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls Universität Heidelberg, Germany
| | 89-03 | In vitro replica of the inner surface of the lungs, for the study of particle-cell interaction
Geiser Kamber M., Prof. Dr., Institute of Anatomy, University of Bern, Switzerland
| | | 139-14 | An in-vitro microvascular model of the endothelial barrier
Herrmann, M., Dr., AO Research Institute Davos, Switzerland
| | 133-12 | Development of an in vitro system to grow and investigate vascular endothelial cells under physiological flow conditions
Rieben R., Prof., Department of Clinical Research, University of Bern, Switzerland
| | 98-05 | Establishment of a murine syngeneic co-culture system of intestinal epithelial cells with intraepithelial T lymphocyte subsets.
Mueller Ch., Prof. Dr., Institute of Pathology, University of Bern, Switzerland
| | 93-04 | Development of a novel multicellular 3-dimensional blood brain barrier in vitro model
Ogunshola O., Dr., Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zürich, Switzerland
| | 81-02 | In vitro model for the testing of endothelial cell activation and damage in whole blood
Rieben R., Prof. Dr., Heart Transplantation Laboratory, Cardiology, University Hospital Bern, Switzerland
| | | 128-11 | Genetic modification of the human airway epithelium – a paradigmatic system to study host responses to human respiratory viruses
Thiel V., PD Dr., Institut für Immunbiologie, Kantonsspital St. Gallen, Switzerland
| | 107-07 | Evaluation of an in vitro model to identify host parameters associated with virulence of Toxoplasma gondii strains
D’Souza S., Dr., Pasteur Institute of Brussels-ISP,1180-Uccle, Belgium
| | 106-07 | Standardization and Pre-validation of MucilAir: A novel in vitro cell model of the human airway epithelium for testing acute and chronic effects of chemical compounds
Huang S., Dr., Epithelix Sàrl, Plan-les-Ouates, Geneva, Switzerland
| | 93-04 | Development of a novel multicellular 3-dimensional blood brain barrier in vitro model
Ogunshola O., Dr., Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zürich, Switzerland
| | 91-04 | Establishment and validation of a Choroid Plexus Model to study drug transport
Fricker G., Prof. Dr., Institute of Pharmacy and Molecular Biotechnology, Ruprecht-Karls Universität Heidelberg, Germany
| | 89-03 | In vitro replica of the inner surface of the lungs, for the study of particle-cell interaction
Geiser Kamber M., Prof. Dr., Institute of Anatomy, University of Bern, Switzerland
| | | | 145-15 | Combining computational modelling with in-vitro cellular responses in order to predict chemical impact on fish growth
Schirmer, K., Prof. Dr., EAWAG, Swiss Federal Institute of Aquatic Science and Technology, Dübendorf, Switzerland
| | | 146-15 | Validation of a novel cell-based approach to study thyroidal physiology: Reduction and/or replacement of experiments with rodents
Sykiotis, G., PhD, Service of Endocrinology, Diabetology and Metabolism, Lausanne University Hospital, Lausanne, Switzerland
| | | 48-96 | Utilization of a model of culture of human intestinal cell lines for the study of the pathogenicity of different strains of Clostridium difficile
Kraehenbuhl J.-P., Prof. Dr., Institut Suisse de Recherches Expérimentales sur le Cancer (ISREC), Switzerland
| | | 146-15 | Validation of a novel cell-based approach to study thyroidal physiology: Reduction and/or replacement of experiments with rodents
Sykiotis, G., PhD, Service of Endocrinology, Diabetology and Metabolism, Lausanne University Hospital, Lausanne, Switzerland
| | | 102-06 | Isolated, autologous blood-perfused heart: Replacement of heterotopic heart transplantation
Bogdanova A, Dr., Institute of Veterinary Physiology, University of Zurich, Switzerland
| | 76-01 | Development of a model of heart angiogenesis in vitro
Battegay E., Prof. Dr., Outpatient Department of Internal Medicine and Department of Research, University Hospital Basel, Switzerland
| | | 118-10 | Engineering of an in vitro hepatocyte tissue system for malaria liver infection research
Mancama D., Dr., Systems Biology, Biosciences Unit, CSIR, South Africa
| | 108-07 | Cultured piscine hepatocytes as an in-vitro source of metabolic clearance data that is currently gleaned by in-vivo bioaccumulation testing in fish
Segner H., Prof. Dr., Centre for Fish and Wildlife Health, Vetsuisse Faculty, University of Berne, Switzerland
| | | 83-02 | The development of an in vitro intervertebral disc organ culture system
Lee C., Dr., Biochemistry and Cell Biology Unit; AO Research Institute, Davos, Switzerland
| | | 107-07 | Evaluation of an in vitro model to identify host parameters associated with virulence of Toxoplasma gondii strains
D’Souza S., Dr., Pasteur Institute of Brussels-ISP,1180-Uccle, Belgium
| | 98-05 | Establishment of a murine syngeneic co-culture system of intestinal epithelial cells with intraepithelial T lymphocyte subsets.
Mueller Ch., Prof. Dr., Institute of Pathology, University of Bern, Switzerland
| | 97-05 | Development of a three-dimensional enteric cell culture model for in vitro studies of the intestinal eukaryotic parasites Cryptosporidium spp.
Mathis A., Prof. Dr., Institute of Parasitology, University of Zürich, Switzerland
| | | 54-96 | Elaboration of an in vitro screening method for testing the effect of drugs and other compounds on the renal transport of uric acid
Roch-Ramel F., Prof. Dr., Institute of Pharmacoly and Toxicology, University of Lausanne, Switzerland
| | | 73-00 | Generation and functional characterization of a clonal murine periportal Kupffer cell line from H-2Kb -tsA58 mice
Landmann R., Prof. Dr., Division of Infectious Diseases, Department of Research, University Hospital Basel, Switzerland
| | | 73-00 | Generation and functional characterization of a clonal murine periportal Kupffer cell line from H-2Kb -tsA58 mice
Landmann R., Prof. Dr., Division of Infectious Diseases, Department of Research, University Hospital Basel, Switzerland
| | 63-97 | In vitro study of pathogenesis of sepsis in a conditionally immortalized Kupffer cell line
Landmann R., Prof. Dr., Division Infectious Deseases, Department Research, University Hospital Basel, Switzerland
| | 43-95 | Short term assay for liver cell activated neurotoxic drugs
Maier P., Prof. Dr., Institute of Toxicology, Swiss Federal Institute of Technology (ETH) and University of Zürich, Switzerland
| | | 143-15 | An advanced in-vitro model of pulmonary inflammation based on a novel lung-on-chip technology
Guenat, O., Prof. Dr., ARTORG Center, University of Bern & Pneumology and Thoracic Surgery Clinics, University Hospital of Bern, Switzerland
| | 128-11 | Genetic modification of the human airway epithelium – a paradigmatic system to study host responses to human respiratory viruses
Thiel V., PD Dr., Institut für Immunbiologie, Kantonsspital St. Gallen, Switzerland
| | 106-07 | Standardization and Pre-validation of MucilAir: A novel in vitro cell model of the human airway epithelium for testing acute and chronic effects of chemical compounds
Huang S., Dr., Epithelix Sàrl, Plan-les-Ouates, Geneva, Switzerland
| | 89-03 | In vitro replica of the inner surface of the lungs, for the study of particle-cell interaction
Geiser Kamber M., Prof. Dr., Institute of Anatomy, University of Bern, Switzerland
| | 82-02 | Magnetic Resonance Imaging (MRI) for the non-invasive assessment of lung inflammation and pulmonary function in the rat
Beckmann N., PD Dr., Novartis Pharma AG Basel
Novartis Institute of Biomedical Research (NIBR), Basel, Switzerland
| | 70-99 | Sensory irritant screening using a stable cell line expressing the vanilloid receptor
Baumann T., Prof. Dr., Dept. of Neurological Suregry,Oregon Health and Sciences University, Portland, USA
| | 46-96 | Development and Validation of an In Vitro Model Simulating Mechanical Ventilation-Induced Inflammation
Pugin J., Dr., Division des Soins Intensifs de Médecine, Hôpital Cantonal Universitaire, Genève, Suisse
| | | | 89-03 | In vitro replica of the inner surface of the lungs, for the study of particle-cell interaction
Geiser Kamber M., Prof. Dr., Institute of Anatomy, University of Bern, Switzerland
| | | 140-14 | Hydrocephalus simulator for testing of active ventriculoperitoneal shunts
Schmid Daners, M., Dr., Institute for Dynamic Systems and Control, Department of Mechanical and Process Engineering, ETH Zurich, Switzerland
| | 134-12 | Cardiovascular simulator with autoregulation
Vandenberghe S,, Prof., ARTORG Center for Biomedical Research, University of Bern, Switzerland
| | | 104-06 | Development of in vitro strategies to propagate and characterize hemotrophic mycoplasmas
Hofmann-Lehmann R., Prof. Dr., Clinical Laboratory, Vetsuisse-Faculty, University of Zurich, Switzerland
| | | 129-11 | The use of microfluidic chambers to study axonal transport in PTEN and SOCS3 dependent axonal regeneration
He Zhigang, Prof., Children's Hospital and Department of Neurology, Harvard Medical School, Boston, MA 02115
| | | 126-11 | Development and validation of a model to investigate myeloid-cell homeostasis
Benarafa C., Dr., Theodor Kocher Institute, University of Bern, Switzerland
| | | 86-03 | Bone Formation in a loading chamber for ex-vivo bone culture
Richards R.G., Dr., AO Research Institute, Davos, Switzerland
| | | 118-10 | Engineering of an in vitro hepatocyte tissue system for malaria liver infection research
Mancama D., Dr., Systems Biology, Biosciences Unit, CSIR, South Africa
| | | 68-99 | Genetic analysis of a 3D in vitro model of the rheumatic pannus tissue
Illges H., PD Dr., Biotechnologie Institut Thurgau an der Universität Konstanz, Switzerland
| | | 67-99 | Human monocyte-derived dendritic cells as in vitro indicators for contact allergic potential of chemicals
Ulrich P., Dr., PCS/GENEX-Experimental Toxicology, Novartis Pharma AG, Basel, Switzerland
| | 65-98 | Reconstructed human epidermis as model for predicting irritancy
Ponec M., Prof. Dr., Skin Research Laboratory, Department of Dermatology, Leiden University Medical Center, Netherland
| | | 61-97 | An in vitro model to study mechanical forces on human venous coronary bypass graft stenosis: Molecular targeting by pharmacological intervention
Lüscher T. F., Prof. Dr., Cardiovascular Research, Institute of Physiology, University Zürich and Cardiology, University Hospital Zürich, Switzerland
| | | 129-11 | The use of microfluidic chambers to study axonal transport in PTEN and SOCS3 dependent axonal regeneration
He Zhigang, Prof., Children's Hospital and Department of Neurology, Harvard Medical School, Boston, MA 02115
| | 121-10 | Organotypic spinal cord slices to study SCI and MS like lesions
Chrast R., Prof. Dr., Department of Medical Genetics, University of Lausanne, Switzerland
| | 120-10 | Development of non-invasive strategies to study corticospinal neuron disease, injury and repair
Jabaudon D., Prof. Dr., Dpt. of Basic Neurosciences, University of Geneva, Switzerland
| | | 146-15 | Validation of a novel cell-based approach to study thyroidal physiology: Reduction and/or replacement of experiments with rodents
Sykiotis, G., PhD, Service of Endocrinology, Diabetology and Metabolism, Lausanne University Hospital, Lausanne, Switzerland
| | 142-14 | Validation of human stem-cell pluripotency using a bioreactor-based culturing system instead of a murine model to effect the development of embryoid bodies into teratomas
De Geyter, C., Prof. Dr., Department of Biomedicine, Department of Biomedicine, University Hospital, University of Basel, Switzerland
| | 132-12 | Identification of predictive in vitro markers of hematopoietic stem cell function
Lutolf M. P., Prof., Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland
| | 117-09 | Embryonic stem-cell-derived in-vitro model of tissue inflammation following confrontation with implant materials
Wartenberg M., Prof. Dr., Friedrich Schiller University Jena and Justus Liebig University Giessen, Germany
| | 115-09 | Engineering of a human brain tumour model to replace animal experimentation
Preynat-Seauve O., Dr., University of Geneva, Switzerland
| | | 144-15 | Development of in vitro three-dimensional multi-cellular culture models to study the role of heterotypic interactions during colorectal carcinomatous invasive process
Rüegg, C., Prof. Dr., Department of OMI, University of Fribourg, Switzerland
| | | 84-02 | Direct cloning of human antibodies from purified specific B-cells
Wirthmueller U., Dr., Institute of Immunology, University Hospital Bern, Switzerland
| | | 98-05 | Establishment of a murine syngeneic co-culture system of intestinal epithelial cells with intraepithelial T lymphocyte subsets.
Mueller Ch., Prof. Dr., Institute of Pathology, University of Bern, Switzerland
| | 92-04 | Adjuvanticity of microbial-derived particles and synthetic analogs in vitro.
Padovan E., Prof. Dr., Instituto Gulbenkian de Ciência, Oerias, Portugal
| | 80-01 | Induction of a primary T cell mediated immune response against drugs and drug metabolites in vitro
Pichler, W.J., Prof. Dr., Division Allergology, University Hospital Bern, Switzerland
| | | 142-14 | Validation of human stem-cell pluripotency using a bioreactor-based culturing system instead of a murine model to effect the development of embryoid bodies into teratomas
De Geyter, C., Prof. Dr., Department of Biomedicine, Department of Biomedicine, University Hospital, University of Basel, Switzerland
| | | 146-15 | Validation of a novel cell-based approach to study thyroidal physiology: Reduction and/or replacement of experiments with rodents
Sykiotis, G., PhD, Service of Endocrinology, Diabetology and Metabolism, Lausanne University Hospital, Lausanne, Switzerland
| | | 115-09 | Engineering of a human brain tumour model to replace animal experimentation
Preynat-Seauve O., Dr., University of Geneva, Switzerland
| | 94-04 | Tumor targeted reporter gene expression to improve and refine traditional models of Tumor growth and metastasis
Vorburger S., Dr., Department of Clinical Research, Visceral and Transplantation Surgery,
University Hospital Bern, Switzerland
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